![]() In this workshop, our expert speakers will lay out strategies that combine next generation technologies in multiplexing chemistry, hardware, and software to achieve increased quantitative performance and throughput efficiency.ĭelivering the best in-class TMT MS 2 quantitation, the Orbitrap Exploris 480 MS for multiplexed proteome analysis utilizes instrument intelligence with Precursor Fit Filter and TurboTMT, ensuring absolute confidence for protein quantification. Increasingly, various biological experiments demand higher multiplexing and sample throughput with accurate quantitation. ![]() Quantitative proteomics strategies using Tandem Mass Tags™ enable precise measurement of protein abundance from multiple samples into a single high-resolution LC-MS analysis. We achieved a more compact footprint using a single turbo-pump with six-stage pumping, which allowed for fewer moving parts, lower electricity consumption, less noise and weight. The highly optimized design permits a compact physical footprint while providing high performance components and many new functionalities that significantly advance performance for many critical application areas. ![]() In addition, to deliver this improved reliability and performance we have improved the Orbitrap, C-Trap, ion-routing multipole and bent flatapole design, also including the source and funnel improvements from the Thermo Scientific Orbitrap Tribrid platform. Not only have we reduced the length of the quadrupole while maintaining ion transmission efficiency, we have included patented configuration switching, meaning the quadrupoles stay cleaner for longer. Focusing on robustness, reliability, performance and size, engineering feedback from customers and service engineers into the Orbitrap Exploris 480 MS was a top priority, leading to a complete instrument design from the ground up based around system usability, as well as technological advancements in pumping technology, control electronics and ion optics.
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